Low Cholesterol levels associated with increased mortality in later life

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You’ve likely heard that high cholesterol is bad for your health, however cholesterol is found in nearly every cell of your body and is vital for optimal functioning. If you have too little, your risk of health problems increases, including all-cause mortality.

Research published in Frontiers in Endocrinology found a revealing link between low total cholesterol (TC) levels and increased mortality risk in those aged 85 and above.1 This research challenges the conventional dogma that lower cholesterol is always better, especially for older adults.

The study, which analyzed data from the Chinese Longitudinal Healthy Longevity Survey, found that individuals with TC levels below 3.40 mmol/L (131 mg/dL) had a significantly higher risk of all-cause mortality compared to those with higher levels.2 In fact, the mortality risk increased by 12% for every 1 mmol/L reduction in TC.3 These findings suggest that maintaining higher cholesterol levels may benefit longevity in your later years.

Why Low Cholesterol Is Harmful in Late Life
Cholesterol, often misunderstood as merely harmful, plays several crucial roles in maintaining bodily functions. This waxy substance serves as a fundamental building block for cell membranes, providing structural integrity and fluidity. It acts as a precursor for various essential hormones and is vital in the production of vitamin D when your skin is exposed to sunlight, contributing to bone health and immune function.

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In your digestive system, cholesterol aids in the formation of bile acids, which are necessary for the absorption of fats and fat-soluble vitamins. Further, cholesterol is integral to myelin sheath formation, enhancing nerve signal transmission throughout your body. A balanced amount of cholesterol is indispensable for optimal health and plays a protective role as you age.

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