39 million Americans take cholesterol-lowering drugs, but a long-hidden study says they may be harmful

For years, we’ve been told that lowering cholesterol is the key to heart health. But what if the entire foundation of that advice was wrong? A long-buried study from the 1960s—the Minnesota Coronary Experiment—suggests exactly that.

This wasn’t some small observational study. It was a five-year clinical trial, conducted in six state mental hospitals and a nursing home, involving 9,423 participants. The setup was simple: one group ate food prepared with seed oils, the other consumed food made with saturated fats. The results? Disastrous for the seed oil group.

As expected, the seed oil group saw their cholesterol levels drop. But here’s the part that changed everything—those same people died younger than the ones eating saturated fat. The data showed that for every 30 mg/dL reduction in cholesterol, the risk of death increased by 22%.

The researchers didn’t like what they found. So they sat on the results. The study wasn’t published until 1989—15 years after it ended. And by then, the anti-saturated fat, pro-seed oil narrative was already locked in place.

Now, consider this: 39 million Americans are taking cholesterol-lowering medications. How many of them are actually shortening their lifespan instead of improving it?

This study should have changed everything. Instead, it was buried.

Sources:

https://www.sciencedaily.com/releases/2025/02/250226142040.htm

https://www.nature.com/articles/d42473-024-00393-9

https://www.bhf.org.uk/informationsupport/heart-matters-magazine/news/behind-the-headlines/cholesterol-and-statins